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The extracellular degradation of GSH occurs on the surface of the cells that express the enzyme -glutamyl transpeptidase and the dipeptidases found in the external plasma membrane (1) (Figure 5)

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Modernas mRNA vaccine is based on a lipid nanoparticle platform, but there are many other emerging nanotechnologies for delivery of nucleic acid vaccines (several structures are shown in Fig

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This shift influences several pathways implicated in neurodegenerative diseases, including energy metabolism, oxidative stress, neuroinflammation, autophagy, and gut microbiota composition (Fig