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Nevertheless, increased IL-1 concentrations have been previously reported to be beneficial as high IL-1 in patients presenting male or unexplained infertility correlated with higher fertilization, implantation, and pregnancy rates ( To the best of our knowledge, this is the first randomized, triple-blind, placebo-controlled clinical trial evaluating the effect of AST supplementation on OS markers, inflammatory cytokines, and ART outcomes in infertile endometriosis patients