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cruzi antigens cross-reacted in vitro with colon and breast cancer cells [74] as well as with intracellular and membranous molecules in lung cancer [76]

Subsequently, live cells were stained with 0.5 M H 2 CDFDA (Invitrogen, Netherlands) to assess ROS level or with 1 M MitoSOX Mitochondrial Superoxide Indicators (Invitrogen, Netherlands) to detect mitochondrial ROS level

While myo-inositol interacts with the PI3K/AKT pathway, which is linked to thyroid carcinogenesis, seleno-enzymes facilitate selenium to prevent the buildup of hydrogen peroxide in the body [23,51]

Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant pancreatic cancer

Z-stacks with a step size of 0.25 m were acquired and the total cell volume was estimated using a custom CellProfiler pipeline, as has been previously reported ( At least 50 cells were analyzed and the cell culture conditions were kept identical to those used for LC/MS analysis