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By month fifteen, the trial's primary endpoint, the average participant had lost 15.2 percent of their starting weight, and the curve had become essentially horizontal [Garvey et al., Nature Medicine, 2022]

[DOI] [PubMed] [Google Scholar] 86.Dawkins MJ, Scopes JW

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This suggests a very good safety and tolerability profile indistinguishable from placebo in those trial settings

By inhibiting this enzyme, 5-Amino-1MQ encourages a return to more efficient fat metabolism and enhanced energy output at the cellular level