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592 CircIPO7 binds with the cytoplasmic Y-box binding protein-1 (YBX1), activating AKT phosphorylation to promote YBX1 nuclear translocation, increasing nasopharyngeal carcinomas resistance to cisplatin treatment

The predominant complaints are GI, manifesting as bloating, flatulence, diarrhea, constipation, and nausea (541, 542)

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