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10.1007/s10875-008-9236-x [DOI] [PMC free article] [PubMed] [Google Scholar] Dawi J., Misakyan Y., Affa S., Kades S., Narasimhan A., Hajjar F., et al

Taken together, Gln metabolism can increase the stemness properties in HCC through activating ROS/Wnt/-catenin pathway, and targeting Gln metabolism, especially GLS1, may be a therapeutic target for the elimination of CSCs

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the rest is mechanistic reasoning that a clinician should weigh individually: Known copper or peptide allergy the most concrete contraindication, explicit enough that clinical researchers screen it out (NCT07437586)