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To determine the efficacy of the treatment, the researchers utilized the Clinical Global Impressions Improvement (CGI-I) scale after the 8-week study period

Botulinum toxin (Botox) injections are FDA-approved for cervical dystonia and spasticity from MS or stroke and are increasingly used for refractory back spasms and myofascial pain syndrome when other treatments have failed

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A final alternative to alleviate FcRn-controlled pathological mechanisms could be to alter FcRn in itself, as may be intended with a gene therapy being developed in a collaboration between Beam and Apellis for a one-time dose of gene-editing molecules targeting FcRn [436, 437]