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In a patient with normal B12 status, injecting more of it does not create surplus energy or burn fat

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A 2021 review published in Nutrients found that GLP-1 receptor agonist use was associated with reduced dietary intake of multiple micronutrients including B12, particularly in patients following calorie-restricted eating patterns, supporting the rationale for monitoring B12 status during treatment even in patients without pre-existing deficiency risk factors

How long you feel the effects can depend on your starting levels, which is why people with a larger deficiency sometimes notice the benefits over a longer stretch

Physical State: Standardized oral tablets for precise experimental protocols