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c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma

Springer-Verlag GmbH Germany, part of Springer Nature: 251263

Songs research on non-small cell lung cancer (NSCLC) found that there is ferroptosis in cancer cells treated with cisplatin, and ferroptosis-resistant cancer cells could secrete miR-4443 through exosomes, which increase the expression of FSP1 in ferroptosis-sensitive cancer cells, thereby enhancing the resistance of the cancer cells to ferroptosis [29]

Early-stage research suggests intranasal dihexa may achieve therapeutic CNS concentrations with minimal systemic exposure, potentially extending the effective half life at the target site (hippocampus) while reducing plasma half life

390 Other clinical studies focusing on providing additional drug options for HR+ advanced breast cancer patients following CDK4/6 inhibitor use are currently ongoing within the realm of PI3K/AKT/mTOR pathway inhibitors