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These findings not only extend our understanding of the function of GR in bacterial metabolic processes and virulence mechanisms but also highlight its significance in the broader context of microbial pathogenicity and stress resistance mechanisms

It can deliver glutathione to the cells efficiently, which improves the utilisation efficiency of glutathione in the body, allowing its physiological functions such as antioxidant and detoxification to be better performed

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This creates a pro-ferroptotic microenvironment for osteoblasts and osteocytes, contributing to abnormal bone remodeling ( Ferroptosis also appears to correlate with OA clinical phenotypes

As an intramuscular (IM) injection, B12/MIC is best administered on either the thigh muscle, or upper arm