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However, CTX is associated with significant reproductive toxicity, which adversely affects the reproductive health of patients undergoing chemotherapy for breast cancer 10,11,12

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Rodrguez et al., 2014

Braiteh F, Correa AM, Hofstetter WL, Rice DC, Vaporciyan AA, Walsh GL, Roth JA, Mehran RJ, Swisher SG , Ajani JA

A robust reversal of cysteine S-glutathionylation modifications was observed across the skeletal muscle proteome, and treated animals demonstrated significantly greater fatigue resistance, muscle mass, and treadmill endurance compared to untreated aged controls