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The authors acknowledge funding support for this publication from Grant Number 13/RC/2073_P2, the Research Ireland CURAM Centre for Medical Devices, which is co-funded by the European Regional Development Fund

Published online January 1, 2001 2,117 View 28 Download Abstract PDF Mitochondrial mutations are associated with a wide range of disorders (Kearns-Sayre and chronic progressive external ophthalmoplegia syndromes, Myoclonic epilepsy and ragged-red fibre disease, Mitoehondrial encephalomyopathy, lactic acidosis, and stroke-like episodes, Leighs disease ancl cerebellar ataxia plus pigmentary retinopathy syndromes), which is inherited maternally

Maggiorini M

Possible mechanisms could be as follows: 1) Some researchers believe that increased GDH activity in the brain is the main cause of neurological impairment

SYTOX cell death assay Macrophages were seeded in a 96-well plate (2.5 10 4 cells per well in 100 L) and incubated at 37 C and 5% CO 2 overnight to allow adherence