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doi: 10.1016/S0044-8486(99)00250-1 288 SpetzA.-L

Unlike stealth liposomes, which rely on the enhanced permeability and retention (EPR) effect for passive accumulation in diseased tissues, active targeting liposomes are functionalized with ligands that bind selectively to overexpressed receptors on target cells

It features, for the first time in a liposomal solution, S-acetyl L-glutathione (SAG), combined with reduced glutathione (GSH), and N-acetyl L-cysteine (NAC)

It is predominantly localized in peroxisomes, into which catalase monomers are imported where heme addition and tetramer formation occur (Lazarow and de Duve 1973)

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