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To broadly recapitulate the regulation of YBX1AMPK axis by -KG availability, we treated human cancer cells with cell-permeable DM-succinate and ITA

These essential amino acids are not produced in the body and are therefore crucial components of a balanced diet

The signs and symptoms of the deficiency may include anemia, the buildup of too much acid in the body (metabolic acidosis), frequent infections, and symptoms caused by problems in the brain including seizures, intellectual disability, and loss of coordination (ataxia)

The whipped texture melts in easily, giving skin lasting hydration without a heavy, sticky feel, making it ideal for everyday use

ABC transporters Drug efflux mediated by ABC transporters is a key mechanism underlying chemoresistance in cancer cells