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It highlights the pathological processes through which gut microbiota dysbiosis exacerbates systemic inflammation and lung injury via multiple pathways, including alterations in metabolites (such as bile acids and tryptophan), inhibition of the anti-inflammatory pathway mediated by the vagus nerve, and activation of TLR signals in the lungs by circulating toxins

The inclusion of glutathione in both clinical treatments and over-the-counter wellness products reflects growing recognition of its role in supporting long-term health and quality of life

Following treatment completion, patients with TB-DM frequently require more extensive long-term care due to their challenges with managing blood sugar levels, elevated risk of cardiovascular disease, and potential for kidney damage ( DM also affects another important nexus to TB control: the transmission cascade

Sokolov AV, Chekanov AV, Kostevich VA, Aksenov DV, Vasilyev VB, Panasenko OM