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We have summarized in this review the known oxidative modifications affecting cysteine residues of the enzymes involved

Commun Med 5 , 420 (2025)

In addition, glutathione S-transferase Pi 1 (GSTP1) facilitates SSG of selected substrates in specific cellular contexts 11

Small human studies support the biological plausibility of both approaches, but there are no robust head-to-head clinical trials proving that one produces better health outcomes than the other