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Deep brain stimulation in early-stage Parkinson disease: Five-year outcomes

38 , BSR20171440, (2018)

Two of the nsSNPs (rs2978663 and rs8190955) identified were also found to be associated with obstructive heart defects (OHDs) and hereditary anemia

When cells face oxidative stress, electrophiles or ROS oxidize specific reactive cysteine residues on Keap1 (e.g., Cys151), inducing a conformational change that prevents Nrf2 ubiquitination