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Affected dogs may present with weakness, ataxia, disorientation, behavioural changes, collapse or seizures

Methotrexate exacerbates NAFLD by inhibiting antioxidant activity, boosting lipid buildup, and generating mitochondrial dysfunction, which leads to increased hepatocyte apoptosis and inflammation

Simvastatin combined with resistance training improves outcomes in patients with chronic heart failure by modulating mitochondrial membrane potential and the Janus Kinase/Signal transducer and activator of Transcription 3 signaling pathways

Both the budesonide and midazolam simulations were greater than twofold relative to the observed

Modification and functional inhibition of regulator of G-protein signaling 4 (RGS4) by 4-hydroxy-2-nonenal