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Critical unresolved issues include identifying the molecular switches that govern the transition of autophagy from an anti- to a pro-ferroptotic state, elucidating subtype-specific differences in crosstalk mechanisms, and clarifying the molecular basis underlying proteins such as COX7A1 to exhibit opposing functions

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Since Ruminiclostridium 6 was only observed in the LD control group, it was unsurprising that its relative abundance was significantly greater in this group compared to all other experimental groups (Supplementary Fig

doi: 10.1186/s12953-019-0155-y