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Description

To characterize immune aging in killifish, we used single-cell RNA sequencing, cytometry and functional in vitro assays on kidney marrow cells from young-adult and old killifish, together with proteomic profiling of both kidney marrow-derived cells and plasma

Ibudilast is an anti-inflammatory drug that is administrated orally and inhibits cyclic nucleotide phosphodiesterases, macrophage migration inhibitory factor, and toll-like receptor 4