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As for the different sex-related activities of metabolizing enzymes, the specific activity of the catabolic enzyme gamma-glutamyltranspeptidase in female mice was 73% of that in male mice, suggesting that the faster glutathione turnover in males could account for the higher susceptibility to oxidative injury [64]

Contralateral Breast Cancer in BRCA1 and BRCA2 Mutation Carriers

Nakayama et al., 2023

This paper provides a theoretical framework for understanding and potentially treating VaD-related neuronal injury through the investigation of ferroptosis mechanisms, the biological functions of HO-1, and its role in regulating ferroptosis