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In brief, isopentenyl-pyrophosphate (IPP) is required for the synthesis of selenoproteins, including GPX4, and the isopentenylation of selenocysteine-tRNA stabilizes selenocysteine-specific tRNAs, contributing to ferroptosis suppression 105,127

Dhillon 1 , Caroline C

These findings suggest that glutathione dysfunction may be closely associated with neurodegenerative processes

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