glutathione peroxidase hydrogen peroxide GPX1 and Its Dichotomous Roles in Cancer Reactive oxygen species clearance |

Phospholipid transfer protein augments apoptosis in THP-1-derived macrophages induced by lipolyzed hypertriglyceridemic plasma

The atherogenic effect of excess methionine intake

Regulation of immune responses by tuft cells

Additionally, some studies, such as those involving oral doses of PBF-677 in healthy volunteers, employed dose-escalation methodologies to determine the maximum tolerated dose while closely monitoring for potential side effects (NCT02639975)

However, despite encouraging preclinical and limited clinical evidence, its clinical translation remains constrained by poor oral bioavailability and a complex pharmacokinetic profile