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A.KellyC.AndradeG.NestadtP.et al

Cluster 2 (T2, T5-T6, T10, T14) exhibits a distinct phytochemical profile, characterized by: (i) higher phenolic acid content relative to other clusters, with p -coumaric acid being particularly abundant, and (ii) reduced levels of all curcuminoids except curcumin I

Piperine has been shown to prevent the degradation of curcumin and increase its concentration in aqueous solution by interacting with and inhibiting P-glycoprotein and glucuronidation in the liver and intestine, improving its bioavailability by up to 2000% (Singh et al., 2013