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To achieve a power of 80% at = 0.05, we estimated that a minimum of 16 cases and 32 controls would be required

End points The primary end points included the occurrence of solicited AEs during the supplementation period and unsolicited AEs within the 28 days following the start of supplementation

Skin reactions: Skin rash and nausea have been reported with oral supplementation [29]

While you can get it through animal-based foods like beef, pork, poultry, fish, and dairy, its also available in supplement form, says Morgan Walker, RD, a dietitian at Lebanon Valley College

Psychosom Med 66:276282 Veronese N, Stubbs B, Solmi M, Ajnakina O, Carvalho AF, Maggi S (2018) Acetyl-l-carnitine supplementation and the treatment of depressive symptoms: a systematic review and meta-analysis