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Common Side Effects These side effects are typically mild and improve as your body adapts: Nausea and vomiting A common side effect, especially when increasing dosage

Frequency: Inject once daily subcutaneously

Analysis of the data indicates that short-term treatment with RM-493 increased resting energy expenditure significantly (by 6.4% vs placebo), thus suggesting RM-493 may be clinically effective for treating obesity

22,149,150 TSC1 acts as a regulator of the stability of TSC2, preventing the degradation of TSC2, while TSC2 is a GTPase activating protein (GAP) that inactivates Rheb, a GTPase of the Ras family, and other small G proteins

(February 2014)