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Oxidative stress injury and glucolipotoxicity in type 2 diabetes mellitus: the potential role of metformin and sitagliptin

Data were acquired using an MS3-based TMT method using the following scan parameters: scan sequence began with an MS1 master scan (Orbitrap analysis, resolution 120,000, 4001700 m/z, RF lens 60%, automatic gain control [AGC] target 2E5, maximum injection time 50 ms, centroid mode) with dynamic exclusion enabled (repeat count 1, duration 15 s)

Therefore, future large-scale, multicenter RCTs with extended follow-up periods are urgently needed to rigorously evaluate the long-term efficacy, safety, and durability of -3 PUFAs in the PCOS population, thereby providing more robust evidence for their clinical application

Pathophysiology of emphysema and implications