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From boosting energy levels and supporting cognitive function to protecting nerve health and stabilizing mood, the benefits can be life-changing for those who need them

Acknowledgements The authors would like to thank Dale Alexander, DO for his contributions

Not everyone taking tirzepatide will need B12 supplementation

A previous study reported that TFR2 is present in ~26% of colon cancer types (38)

A result within the normal range (typically around 133675 pmol/L, though this varies by laboratory) generally indicates adequate vitamin B12 status , though symptoms may occasionally occur even with borderline-normal levels, particularly in individuals with increased metabolic demands or early neurological involvement