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Med Hypotheses (1980) 6(11):112333

Paired box 6 (PAX6) is a DNA-binding transcription factor that downregulates the expression of the vascular endothelial growth factor A (VEGFA) gene in glioma cells to suppress tumor cell invasion

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Preventive management includes avoiding triggers and using migraine prophylactic medication, which can include 69 : Beta-blockers Tricyclic antidepressants Anti-seizure medications Serotonin-norepinephrine reuptake inhibitors (SNRIs), particularly when vestibular symptoms predominate (can worsen headaches) Verapamil, when vertigo manifests in the context of migraine aura For acute attacks of vertigo, the following vestibular suppressants can be considered 69 : Antihistamines Antiemetics Benzodiazepines Mnire Disease Initial therapy in Mnire disease should be dietary and lifestyle adjustments