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Description

Every protocol includes a clinical consultation, structured dosing cycles, and ongoing monitoring

The committee makes recommendations to the FDA rather than approving the peptides itself

Lin R, Lang M, Heinsinger N, Stricsek G, Zhang J, Iozzo R, Rosenwasser R, Iacovitti L

Signal Transduction Targeted Ther (2018) 3:110

This represents a potential caveat for the translation of preclinical into clinical research, which is further emphasized by the well-documented differences in responses to medication across ALS phenotypes (164)