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It upregulates genes involved in repair, antioxidant defense, and stem cell function while downregulating genes associated with inflammation, fibrosis, and tissue destruction

261,262 Wnt, a key signaling molecule in the Wnt/-catenin pathway, is also an important protein in the repair process of intestinal epithelial mucosal injury

It lowers the risk of stroke, heart disease, and anemia

Side effects Despite FDA approval, PHEN/TPM is not approved for obesity pharmacotherapy by the EMA due to cardiovascular safety concerns

the only human-relevant context in which it appears is as a prohibited doping agent , and its use in racehorses is an illegal abuse , documented here as a warning rather than a practice to follow [6]