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Enhanced levels of circulating malondialdehyde has been observed in the advanced stages of breast cancer as compared to early stages, which shows differences in the stage of oxidative stress

These complexities underscore the need for tailored redox-sensitive nanocarrier design to achieve optimal therapeutic precision (140)

This intelligent hydrogel enables responsive release of H2O2 in the tumor microenvironment by specifically targeting the CD44 receptor on the surface of tumor cells

Consequently, there is a need for long-term studies with more substantial participant numbers to verify the sustained effectiveness of NADH and CoQ10 in treating ME/CFS [129]

In cancer cells, lactylation is commonly associated with the upregulation of gene expression to promote cancer progression, which is consistent with the phenotypes resulting from lactate accumulation [135,136]