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A large randomized trial in older adults found no effect of EPA and DHA on cognitive function, and the broader trial record shows little benefit in cognitively healthy people or in established Alzheimers, with a possible signal in early cognitive impairment and in people who do not carry APOE4

To really maximize the macrophage polarization and ECM remodeling effects of these peptides, you should combine them with a restorative lifestyle approach: 1

Products containing bitter melon, cinnamon, fenugreek, or other herbs that may affect glucose metabolism or gastric motility should be discussed with the prescribing provider, as additive effects with tirzepatide are possible

Control of human hair growth by neurotrophins: brain-derived neurotrophic factor inhibits hair shaft elongation, induces catagen, and stimulates follicular transforming growth factor 2 expression