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[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Xie K., Liu Y., Li X., Zhang H., Zhang S., Mak H.Y., Liu P

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Unlike many other antioxidants that we must get primarily from our diet (like Vitamin C or Vitamin E), our bodies actually produce glutathione naturally within the liver and nearly every other cell

6.2 Linking GSH/GSSG to Transcriptomic and Proteomic Regulation Transcriptomic and proteomic data can connect metabolite changes to functional modules: GCLC/GCLM/GSS for synthesis, SLC7A11 for substrate acquisition, GSR/GPX/GST for regeneration and use, pentose phosphate pathway enzymes for NADPH supply, and NRF2-KEAP1 signaling for coordinated antioxidant adaptation

Dale, G