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4T1 cells were seeded into 6-well plates at a density of 6000 cells per well and divided into 3 groups including control (untreated), Bi 2 S 3 (Bi: 60 g mL 1 ), and Bi 2 S 3 -3BP (Bi: 60 g mL 1 , 3BP: 10 g mL 1 )

Nevertheless, the combination of PHA with nutraceuticals (SE and AST) elicited more favorable effects in all measured parameters and histological findings, compared to other treated groups

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S20), which was consistent with the results reported in the literature [46]

Intermediates of methylation and demethylation may play important roles in disease-related transcriptional plasticity 76,80,81