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Some drugs, including proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RAs) are acid-inhibiting, impairing the release of dietary B12 from food proteins, thus producing risk of B12 deficiency (Lam et al., 2013)

Individuals with this variant may have higher homocysteine levels and an increased risk of certain conditions, particularly when B vitamin status is inadequate

Table of Contents Why Thigh Numbness Can Occur After Gastric Sleeve Surgery Nutritional Deficiencies Linked to Nerve Symptoms Post-Surgery Other Causes of Thigh Numbness Following Bariatric Procedures When to Seek Medical Advice About Numbness After Weight Loss Surgery Diagnosis and Assessment: What Your NHS Team May Recommend Managing and Recovering From Post-Operative Thigh Numbness Frequently Asked Questions Why Thigh Numbness Can Occur After Gastric Sleeve Surgery Thigh numbness after gastric sleeve surgery most commonly results from compression of the lateral femoral cutaneous nerve during prolonged surgical positioning or from rapid weight loss reducing protective fat padding around nerve pathways

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