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In the small intestine, VIC exists as ascorbate (predominant) and DHA, which is reduced to the ascorbate form in cells

Lavelle and Sokol, 2020)

143 Unlike HIF1A, endothelial PAS domain protein 1 (EPAS1, also known as HIF2A) appears to promote ferroptosis in clear cell carcinoma cells through transcriptional upregulation of hypoxia-inducible lipid droplet-associated (HILPDA/HIG2), 144 a regulator of enriched lipids that contains polyunsaturated fatty acyl side chains

Antioxidants are nutrients that help to protect your body from the damage caused by free radicals - the toxic molecules that play a role in the development of diseases from cataracts to heart disease to arthritis