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As the tumor progresses, tumor cells may enhance glucose uptake and utilization while also relying on other metabolic pathways for energy production, such as fatty acid oxidation and protein metabolism

[DOI] [PMC free article] [PubMed] [Google Scholar] 420

Recall that the 4-OH metabolites can increase risk for certain cancers, such as breast and prostate cancer, through their DNA-damaging effect

The researchers gave nine healthy men between the ages of 19 and 38 a drink containing six grams of arginine or a placebo drink without active ingredient