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Since that COVID-19 exhibits unusual symptoms including GSH depletion, GPX4 inactivation, abnormal iron metabolism, and elevation of PUFA peroxidation by reactive oxygen species, it is possible that SARS-CoV-2 might cause ferroptosis in the dopaminergic neurons, which would then contribute to PD

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It also has downstream effects on cell proliferation, migration, and apoptosis among various vascular cell types in a time-and stage-specific manner, leading to changes in the extracellular environment that lead to pulmonary vascular dysfunction, which in turn causes PH (92)

10.1111/mve.12068 20 BarbosaP