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Preparation of the PURE G4 -LA 12 -anti- GLS1 -siRNA dendriplex In order to improve the efficacy of the dendriplex PURE G4 -LA 12 -anti- GLS1 -siRNA formation, since 24 negatively charged lactate molecules (LA groups) can reduce the availability of amine groups on the surface of the dendrimer and interfere with siRNA binding and stability, a new nanoparticle with 12 LA groups on the surface was used

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The treatment has the power to shape the lower facial features

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