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Alpha Arbutin a gentle brightening agent that helps with the appearance of uneven pigmentation

MIF also contributes to the polarization of macrophages toward a pro-inflammatory M1-like profile, yet its ultimate effect depends on the NF-B mediated balance between proand antitumor functions (104)

Keap1 is rich in cysteine residues, acting as a sensor constantly monitoring OS levels in the cytosol [58]

Total RNA was extracted from with Trizol reagent (Beyotime, Shanghai, China) according to the manufacturers instructions

Additionally, to address complex diseases, some studies also employ co-expression or fusion expression strategies