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Two molecules, GHK and securinine topped the list and were selected out of 1,309 bioactive molecules as the best agents capable to reverse expression of 54 gene sets overexpressed in malignant invasive metastatic colon cancer, which included node molecules YWHAB, MAP3K5, LMNA, APP, GNAQ, F3, NFATC2, and TGM2, involved in regulation of multiple biochemical pathways [ 27 ]

The findings corroborated that the levels of antioxidants, such as albumin, HDL-C, zinc, and total antioxidant capacity, were decreased, whereas serum peroxides and free radicals were elevated in individuals with MDD compared with those in the control group [126]

The Huaier group demonstrated a significantly higher RFS rate compared to the control group (62.39% vs

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