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Molecular dynamics simulations, surface plasmon resonance experiments, and pseudovirus cell entry assays showed decreased SARS-CoV-2 binding affinity to the human ACE2 receptor at higher temperature (40C vs

It is possible that we only detected cytoplasmic GPX4 because of its abundant endogenous distribution compared with that of mitochondrial or nucleolus GPX4

Similarly, lipid ROS can enhance GSDMD cleavage by activating CASP1 in macrophage [143]