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PD and several related neurodegenerative disorders can also been considered as proteinopathies, in which the core neurodegeneration of nigrostriatal dopaminergic neurons in PD is also associated with a more widespread cellular deposition of alpha-synuclein 8

The actual peer-reviewed article has yet to be published

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A low-residue diet limits fiber and other substances to reduce stool volume

68 Similarly, deletion of Atg7 or LAMP2 leads to cardiomyopathy with mitochondrial defects, 67 thus emphasizing the vital link between autophagy and mitochondrial health