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Vincristine and paclitaxel affect large, myelinated fibers, while cisplatin damages all types of myelinated fibers, and bortezomib affects small, unmyelinated fibers (Boehmerle et al., 2014

62 Brain biochemistry, metabolism, and functions, including glucose uptake and energy consumption, oxidative tissue stress, cholinergic deficiency, and cognitive capacities, are severely and persistently impacted by ICV treatment with STZ

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