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Description

This approach has revealed pronounced spatial heterogeneity in the expression of INS and other key genes, not only between donors but also across different pancreatic lobes and even between individual islets within the same anatomical region

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Its pro-apoptotic mechanism also involves suppression of fasciclin-like arabinogalactan protein-mediated Jun N-terminal kinase (JNK) signaling, leading to increased BAX/Bcl-2 ratio (31)

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DP activates the Nrf2-mediated ferroptosis signaling pathway to mitigate high glucose-induced damage Western blot analysis (Fig

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IL-1 is a core member of the IL-1 family, encoded by the IL1B gene

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