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This pathway is defined by the aggregation of lipoylated mitochondrial proteins and destabilization of Fe-S clusters, ultimately leading to proteotoxic stress and mitochondrial dysfunction

is supported by a Singapore Ministry of Education start-up Grant (MOE#022388-00001) and by a core grant from A*STAR to A*STAR Infectious Diseases Labs

Its primary clinical discussion centers on its role in telomere biology, where research suggests it may influence telomerase activity, the enzyme responsible for maintaining telomere length

Ahmed N, Thornalley PJ, Luthen R, et al

A survey about methods and recent advances in cancer diagnostic and therapy