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Description

Some functions that choline serves in the body are: Production of sphingomyelin and phosphatidylcholine, which are needed to maintain cell membrane integrity

Acute symptoms such as fatigue may improve within days, whilst neurological symptoms like paraesthesia typically require weeks to months of treatment

In addition, the concentration of 5MTHF in the CSF is lower than normal in patients with idiopathic cerebral folate deficiency, and some patients also have reduced concentrations of CSF 5-hydroxyindoleacetic acid and biopterin