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In this context, it has previously been proposed that mitotic chromosomal compaction can occur through a condensin-independent mechanism, including post-translational modifications of histones, particularly histone deacetylation 71,72,73

Though this layer is not a primary vulnerable site in AMD, thinning has been reported in dry AMD patients (Yenice et al., 2015) and as a consequence of retinal remodeling following photoreceptor degeneration (Kortuem et al., 2000)

Its best to temporarily pause taking things like Aspirin , Ibuprofen (you might know it as Advil or Motrin), Naproxen (Aleve), or any other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)