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A cross-sectional study showed that serum levels of 8-hydroxydeoxyguanosine, which is a marker of oxidative DNA damage, were significantly higher in individuals with OCD than in those without OCD and were lower in the patients who received treatment for OCD [7]

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Namenda (memantine HCl) acts as an N-methyl-D-aspartate (NMDA) receptor antagonist designed to limit glutamate excitotoxicity and resulting neuronal damage [19,22,23]

In fact, participants with OCD had significantly higher levels of Glu and lower levels of GABA in the ACC and a higher Glu:GABA ratio in that region